Endocrine Abstracts

Introduction: Cushing’s disease (CD) is a rare but serious pathology in children and adolescents. It differs from adult pathology by the mode of presentation and management. We report a case of CD in a 14-year-old child whose diagnosis was confirmed only after 2 years.Observation: This was a 14-year-old female patient with a family history of consanguineous marriage and personal history of nephrotic syndrome who presented with delayed stature, delay...

Introduction: Congenital hypothyroidism is 30 times more frequent in newborns with Down syndrome (DS) than in the population of healthy children. Mild isolated TSH elevation with normal thyroxine (T4) levels is the most commonly seen pattern of thyroid dysfunction in these children.Patients and methods: A retrospective study was carried out on eleven patients with DS in the pediatric department of Mahdia who were followed for congenital hypothyroidism.</...

Background and Aims: Acute and chronic infectious diseases appear to be more prevalent among patients having diabetes mellitus. Infections associated with diabetes could be particularly serious increasing morbimortality and treatment costs. Diabetic patients’ predisposition to infections could be explained by the hyperglycemic environment impairing immune function. Other factors my contribute such as degenerative complications, for example autonomic neuropathy could decre...